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Ethical dilemmas

Code of ethics in action: vignettes from ISBT congresses

Code of Ethics

Did you know that the ISBT has a Code of Ethics related to Transfusion Medicine?

This document outlines the basic ethical principles of dignity, autonomy, beneficence, non-maleficence (not doing harm), and justice, and how they apply to blood donors, recipients, and the stewardship of the blood supply. The Code of Ethics was first developed in 1980, updated in 2017 and is currently undergoing revision. It is available in eight languages and can be found on the ISBT website.

At the ISBT Congresses in Gothenburg (2023), Barcelona (2024), and Milan (2025), members of the ISBT Standing Committee on Ethics—supported by Working Party members—presented clinical vignettes illustrating ethical challenges in transfusion medicine. During the sessions, audience members engaged in live voting on questions related to these scenarios. Now, you can participate too by completing the quiz below.

Vignettes will be published in the coming Transfusion Today issues. In these cases, you will have a chance to reflect on your practice, compare with others completing the quiz, and see some points to consider when making decisions.

Vignette 4. Lookback

The case

A 33-year-old woman gave birth in your hospital 5 years ago. After delivery, her hemoglobin was 80 g/L and she received a unit of red blood cells. The blood bank has now received a lookback notice from the blood centre that supplied the unit: the donor of the red cell unit has now returned to donate and has tested HIV positive. This donor had been tested at the time of donation and was HIV negative but had not returned to donate since then.

As the person responsible for the hospital blood bank, what would you do?

Submit your answers through the below survey:

Click the below button to see what others think. The page will show you the accumulative results.

Click here to see the results

Discussion points

Procedures as to who should inform a patient that the donor of their blood component is now testing positive for a transfusion transmissible infection may vary in different jurisdictions and circumstances. For example, the name of the patient’s family physician may or may not be available to the blood bank. It is also possible that the hospital blood bank or obstetrics unit is aware that the patient had a negative HIV test years after the possibly infected transfusion, for example, when she was readmitted for a second delivery two years later; in such a case, the patient clearly was not infected by the earlier transfusion and there is no value in patient notification.

The Code of Ethics provides general guidance about beneficence and nonmaleficence related to patients: Patients should be informed if information becomes available following a transfusion that indicates they have, or may have been, harmed by the transfusion. Guidelines about transfusion thresholds and situations when transfusions are indicated have evolved over time, as more evidence is available from high quality randomized clinical trials. Medical records may not always provide a full picture of the patient’s clinical situation at the time of transfusion. As mentioned above, the Code of Ethics specifies that “decisions relating to transfusion of blood should be based on the best available evidence and treatments for patients”, however, there is no mention made about informing patients that different decisions could have been made about their past treatment.

The Author

Vignette 4 is presented by Naomi Rahimi-Levene, member of the Standing Committee on Ethics and Director of the Blood Bank and a Senior Hematologist at the Shamir Medical Center in Zerifin, Israel.

If you can't get enough of these ethical issues...

In the April and July 2025 issues of Transfusion Today, the first ethical vignettes were published. Click the button to read about the first two cases, complete the polling questions and see what other think about the ethical issues.

Take me to vignette 1
Take me to vignette 2
Take me to vignette 3

Did you know?

The Standing Committee on Ethics (SCE) gives advice or opinion on ethical issues as requested and directed by the ISBT Board of Directors. ISBT members can submit (ethical) issues, however, the Board of Directors decides whether or not the SCE will work on the submitted issues. The SCE has a broad international representation and comprises individuals who have experience or an interest in ethics.

Read more about the committee and its work here.

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